Conduct experiments to identify and validate drug targets. Support assay design, optimization, validation, and data analyses. Design and execute molecular and cell biology experiments. Troubleshoot and analyze complex data in support of drug discovery projects. Presentation of results and conclusions both orally and written. *** is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status. Being on a temporary contractor assignment at *** means working in an innovative culture where you have the opportunity to support the work of thousands of others around the globe dedicated to improving the lives of others. *** discovers and brings life-changing medicines to those who need them, improves the understanding and management of disease, and gives back to communities through philanthropy and volunteerism. Client passionately promotes food security and fosters the human-animal bond to enrich the lives of its customers and the customers they serve as well. Our values: integrity, excellence, respect for people. Greater than 90% of workers rate their *** assignment as above average or excellent.
Qualifications:
Contractor, Obesity Research - Boston
we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees around the world work to Client and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world
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The Cardiometabolic Renal Therapeutic Area (CMR) of Client and Company focuses on the discovery of biologic, small molecule and genetic therapeutics for the treatment of diabetes, obesity and associated complications.
We are seeking a skilled and motivated individual who can contribute to a successful drug discovery and development team in the Obesity research group in Cambridge. The successful candidate will leverage their strong in vivo pharmacology background and complementary laboratory skills to play a critical role in supporting discovery efforts and established pipeline projects with an emphasis on anti-obesity therapeutics. You will be responsible for executing on critical capabilities in the laboratory setting and working with other scientists within and across departments to achieve project and department goals.
Key responsibilities include:
• Plan and independently execute in vivo experiments to support preclinical characterization and evaluation of targets/pathways that regulate energy balance.
• Perform routine rodent handling, dosing via multiple routes of administration (including but not limited to PO, IP, SQ, IV), blood collection (including cardiac puncture), perfusion, and tissue collection.
• Conduct metabolic assessments, including food intake measurements, glucose tolerance tests (GTT), and insulin tolerance tests (ITT).
• Perform molecular and biochemical assessments on ex vivo samples.
• Function independently while working within a team-oriented lab environment and cross-functional project teams.
• Maintain accurate records, independently analyze data, and report data in written and oral formats. Perform all work in full compliance with *** Research Policies and complete all required training activities in the timeframe specified.
Minimum qualifications:
• B.S. and/or M.S. in biology or a closely related field with 3+ years of laboratory experience.
Additional Skills/Preferences:
• A background in the biology and physiology of energy balance regulation and metabolic disease is a plus.
• Experience with immunohistochemistry, brain sectioning, and confocal or fluorescence microscopy imaging is a plus.
• Demonstrated ability to work on cross-functional teams and projects.
• Strong communication skills and experience presenting data in a team environment.
Nesco Resource offers a comprehensive benefits package for our associates, which includes a MEC (Minimum Essential Coverage) plan that encompasses Medical, Vision, Dental, 401K, and EAP (Employee Assistance Program) services.
Nesco Resource provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws.
